Quantum dots light emitting devices on MEMS: microcontact printing, near-field imaging, and early cancer detection

Ashwini Gopal; Kazunori Hoshino; John X. J. Zhang

doi:10.1117/12.901089

8 September 2011 Quantum dots light emitting devices on MEMS: microcontact printing, near-field imaging, and early cancer detection

Ashwini Gopal, Kazunori Hoshino, John X. J. Zhang

Author Affiliations +

Proceedings Volume 8191, International Symposium on Photoelectronic Detection and Imaging 2011: Sensor and Micromachined Optical Device Technologies; 819106 (2011) https://doi.org/10.1117/12.901089
Event: International Symposium on Photoelectronic Detection and Imaging 2011, 2011, Beijing, China

Abstract

Controlled patterning of light emitting devices on semiconductors and micro-electro-mechanical systems (MEMS) enables a vast variety of applications such as structured illumination, large-area flexible displays, integrated optoelectronic systems and micro-total analysis systems for real-time biomedical screening. We have demonstrated a series of techniques of creating quantum dot-based (QD) patterned inorganic light emitting devices at room temperature on silicon (Si) substrate. The innovative technology was translated to create localized QD-based light sources for two applications: (1) Three-dimensional scanning probe tip structures for near field imaging. Combined topographic and optical images were acquired using this new class of "self-illuminating" probe in commercial NSOM. The emission wavelength can be tuned through quantum-size effect of QDs. (2) Multispectral excitation sources integrated with microfluidic channels for tumor cell analyses. We were able to detect the variation of sub-cellular features, such as the nucleus-to-cytoplasm ratio, to quantify the absorption at different wavelength upon the near-field illumination of individual tumor cells towards the determination of cancer developmental stage.

Citation Download Citation

Ashwini Gopal, Kazunori Hoshino, and John X. J. Zhang "Quantum dots light emitting devices on MEMS: microcontact printing, near-field imaging, and early cancer detection", Proc. SPIE 8191, International Symposium on Photoelectronic Detection and Imaging 2011: Sensor and Micromachined Optical Device Technologies, 819106 (8 September 2011); https://doi.org/10.1117/12.901089

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