Removing skin micro-vessels using photo-mediated ultrasound therapy: a study on the chicken wattle model

Mingyang Wang; Rohit Singh; Yannis M. Paulus; Xinmai Yang; Xueding Wang

doi:10.1117/12.2650119

17 March 2023 Removing skin micro-vessels using photo-mediated ultrasound therapy: a study on the chicken wattle model

Mingyang Wang, Rohit Singh, Yannis M. Paulus, Xinmai Yang, Xueding Wang

Author Affiliations +

Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520H (2023) https://doi.org/10.1117/12.2650119
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Cutaneous vascular malformations (CVM), such as port wine stain (PWS), often appear in highly visible parts of patient and cause emotional and social problems. In this work, we utilized our novel anti-vascular technique, termed photo-mediated ultrasound therapy (PUT), which combines nanosecond duration laser pulses synchronized with ultrasound bursts to treat blood vessels. The feasibility of PUT in the treatment of cutaneous microvessels was evaluated in a chicken wattle model in vivo. The treatment results showed perfusion stop in microvessels up to 1.5mm deep in chicken wattle, as demonstrated by both the OCT angiography and the color change in skin images after the treatment. The treatment effect and safety such as epidermal tissue damage and inflammation were also evaluated by H&E histology.

Conference Presentation

Citation Download Citation

Mingyang Wang, Rohit Singh, Yannis M. Paulus, Xinmai Yang, and Xueding Wang "Removing skin micro-vessels using photo-mediated ultrasound therapy: a study on the chicken wattle model", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520H (17 March 2023); https://doi.org/10.1117/12.2650119

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE