Non-invasive and label-free zebrafish investigations using polarization-sensitive optical coherence tomography (Conference Presentation)

Antonia Lichtenegger; Junya Tamaoki; Pradipta Mukherjee; Roxane Licandro; Lida Zhu; Tomoko Mori; Rion Morishita; Lixuan Bian; Ibrahim Abd El-Sadek; Shuichi Makita; Konrad Leskovar; Satoshi Matsusaka; Martin Distel; Makoto Kobayashi; Bernhard Baumann; Yoshiaki Yasuno

doi:10.1117/12.2646760

16 March 2023 Non-invasive and label-free zebrafish investigations using polarization-sensitive optical coherence tomography (Conference Presentation)

Antonia Lichtenegger, Junya Tamaoki, Pradipta Mukherjee, Roxane Licandro, Lida Zhu, Tomoko Mori, Rion Morishita, Lixuan Bian, Ibrahim Abd El-Sadek, Shuichi Makita, Konrad Leskovar, Satoshi Matsusaka, Martin Distel, Makoto Kobayashi, Bernhard Baumann, Yoshiaki Yasuno

Author Affiliations +

Proceedings Volume PC12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023; PC123910Z (2023) https://doi.org/10.1117/12.2646760
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The zebrafish has shown to be an essential preclinical animal model, especially in the field of oncology. A non-invasive, high-resolution, and three-dimensional imaging modality is required to identify disease related changes in this model organism. The presented polarization-sensitive Jones matrix optical coherence tomography (JM-OCT) prototype was utilized in three different studies, covering in vivo imaging of wildtype zebrafish, an adult postmortem tumor model and a longitudinal xenograft tumor zebrafish investigation. This work highlights the potential of JM-OCT as a non-invasive, label-free, and three-dimensional imaging tool for preclinical cancer research based on zebrafish models.

Conference Presentation

Citation Download Citation

Antonia Lichtenegger, Junya Tamaoki, Pradipta Mukherjee, Roxane Licandro, Lida Zhu, Tomoko Mori, Rion Morishita, Lixuan Bian, Ibrahim Abd El-Sadek, Shuichi Makita, Konrad Leskovar, Satoshi Matsusaka, Martin Distel, Makoto Kobayashi, Bernhard Baumann, and Yoshiaki Yasuno "Non-invasive and label-free zebrafish investigations using polarization-sensitive optical coherence tomography (Conference Presentation)", Proc. SPIE PC12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023, PC123910Z (16 March 2023); https://doi.org/10.1117/12.2646760

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available