Illuminating gene expression dynamics by optogenetics

Akihiro Isomura

doi:10.1117/12.2311587

24 April 2018 Illuminating gene expression dynamics by optogenetics

Akihiro Isomura

Proceedings Volume 10711, Biomedical Imaging and Sensing Conference; 107110K (2018) https://doi.org/10.1117/12.2311587
Event: SPIE Structured Light, 2018, Yokohama, Japan

Abstract

Cells receive diverse signaling cues from their environment that trigger cascades of biochemical reactions in a dynamic manner. Live-cell imaging technologies have revealed dynamic patterns of gene activities; however it has been challenging to clarify how such dynamic information is delivered and decoded in complex networks of inter-cellular and inter-molecular interactions. The recent development of optogenetic technology with photo-sensitive proteins has changed this situation. In this talk, we introduce our recent efforts to visualize the flows of dynamic patterns in gene expression dynamics, which utilize methods combining single-cell imaging and optogenetics.

Citation Download Citation

Akihiro Isomura "Illuminating gene expression dynamics by optogenetics", Proc. SPIE 10711, Biomedical Imaging and Sensing Conference, 107110K (24 April 2018); https://doi.org/10.1117/12.2311587

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available