Evaluation of a transparent cranial implant for multi-wavelength intrinsic optical signal imaging

Nami Davoodzadeh; Mildred S. Cano-Velázquez; David L. Halaney; Carrie R. Jonak; Devin K. Binder; Guillermo Aguilar

doi:10.1117/12.2511035

1 March 2019 Evaluation of a transparent cranial implant for multi-wavelength intrinsic optical signal imaging

Nami Davoodzadeh, Mildred S. Cano-Velázquez, David L. Halaney, Carrie R. Jonak, Devin K. Binder, Guillermo Aguilar

Proceedings Volume 10865, Neural Imaging and Sensing 2019; 108650B (2019) https://doi.org/10.1117/12.2511035
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Optical brain imaging based on intrinsic signals has revealed new insights into functional brain activation imaging. The main obstacle to this approach is the highly scattering cranial bone over the cortex which hinders the observation of intrinsic optical signals. We have introduced a novel solution for this limitation by proposing a transparent cranial implant providing long-term optical access to the brain, which we call the Window to the Brain (WttB) implant. In this study, we evaluated the feasibility of the WttB implant for multi-wavelength intrinsic optical signal imaging of the brain.

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Nami Davoodzadeh, Mildred S. Cano-Velázquez, David L. Halaney, Carrie R. Jonak, Devin K. Binder, and Guillermo Aguilar "Evaluation of a transparent cranial implant for multi-wavelength intrinsic optical signal imaging ", Proc. SPIE 10865, Neural Imaging and Sensing 2019, 108650B (1 March 2019); https://doi.org/10.1117/12.2511035

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