6 March 2020Monitoring changes in kidney optical properties during cold storage preservation with spatial frequency domain imaging (Conference Presentation)
Rebecca A. Rowlandhttps://orcid.org/0000-0002-8913-9599,1 Adrien Ponticorvo,1 Alberto Jarrin Lopez,2 Shiri Li,2 Hirohito Ichii,2 Anthony J. Durkin1,3
1Beckman Laser Institute and Medical Clinic (United States) 2Univ. of California, Irvine Medical Ctr. (United States) 3Univ. of California, Irvine (United States)
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Delayed graft function occurs in 40% of kidney transplantation cases, and is not apparent until after surgery has concluded. To understand changes in donor kidney tissue before transplantation, spatial frequency domain imaging (SFDI) was used to measure absorption and reduced scattering coefficients in excised porcine kidneys as they underwent a standard period of cold ischemic time (CIT). SFDI indicated an increase in reduced scattering and absorption. The scattering b parameter increased until 24 hours, then returned towards baseline. These results suggest that continued investigation may lead to the development of a noninvasive assessment for graft viability.
Rebecca A. Rowland,Adrien Ponticorvo,Alberto Jarrin Lopez,Shiri Li,Hirohito Ichii, andAnthony J. Durkin
"Monitoring changes in kidney optical properties during cold storage preservation with spatial frequency domain imaging (Conference Presentation)", Proc. SPIE 11212, Therapeutics and Diagnostics in Urology 2020, 1121209 (6 March 2020); https://doi.org/10.1117/12.2546409
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Rebecca A. Rowland, Adrien Ponticorvo, Alberto Jarrin Lopez, Shiri Li, Hirohito Ichii, Anthony J. Durkin, "Monitoring changes in kidney optical properties during cold storage preservation with spatial frequency domain imaging (Conference Presentation)," Proc. SPIE 11212, Therapeutics and Diagnostics in Urology 2020, 1121209 (6 March 2020); https://doi.org/10.1117/12.2546409