Brain research is a multi-disciplinary endeavor, and inspires the development of innovative measurement tools. Multiphoton microscopy is the go-to technique for high spatial resolution, deep imaging in scattering biological tissue, and relies heavily on the new development of ultrafast lasers that deliver high pulse energy, flexible repetition rate, and wide wavelength coverage. By pushing the boundaries of imaging depth and speed, multiphoton microscopy enables large-scale, non-invasive monitoring of brain activity in live animals, and is poised to play a major role in understanding how brains work.
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