Intraoperative use of optical coherence angiography in ischemic bowel disease: a pilot study

Elena B. Kiseleva; Maxim G. Ryabkov; Mikhail S. Baleev; Alexander N. Vorobyov; Grigory V. Gelikonov; Ivan N. Romanov; Ekaterina V. Gubarkova; Natalia D. Gladkova

doi:10.1117/12.2559615

9 April 2020 Intraoperative use of optical coherence angiography in ischemic bowel disease: a pilot study

Elena B. Kiseleva, Maxim G. Ryabkov, Mikhail S. Baleev, Alexander N. Vorobyov, Grigory V. Gelikonov, Ivan N. Romanov, Ekaterina V. Gubarkova, Natalia D. Gladkova

Author Affiliations +

Proceedings Volume 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine; 114570B (2020) https://doi.org/10.1117/12.2559615
Event: Saratov Fall Meeting 2019: VII International Symposium on Optics and Biophotonics, 2019, Saratov, Russian Federation

Abstract

A method, based on optical coherence angiography (OCA), for the intraoperative diagnosis of blood microcirculation in the ischemic intestine has been tested. The pilot clinical study involved 18 patients who had undergone urgent operations for thrombosis of segments II or III of the superior mesenteric artery, as well as for infringement of the bowel and the mesenteric vessels. In the OCA images regions of preserved blood microcirculation in the intestinal wall were characterized by the presence of branched networks of intramural microvessels and a bright background in the OCA images. Regions of the intestine in which the intramural vessels were interrupted or could not be visualized were considered as potentially non-viable. These data were used to determine the boundaries for intestinal resection. In comparison with the traditional method of intraoperative diagnosis of intestinal blood flow, the use of such OCA criteria meant the volume of bowel resection could be decreased by 21.5 [14.1; 36.0]% (p = 0.037). This observation demonstrates the great potential of OСA in the intraoperative detection of the boundaries of damaged and healthy intestinal wall in ischemic bowel disease.

Citation Download Citation

Elena B. Kiseleva, Maxim G. Ryabkov, Mikhail S. Baleev, Alexander N. Vorobyov, Grigory V. Gelikonov, Ivan N. Romanov, Ekaterina V. Gubarkova, and Natalia D. Gladkova "Intraoperative use of optical coherence angiography in ischemic bowel disease: a pilot study", Proc. SPIE 11457, Saratov Fall Meeting 2019: Optical and Nano-Technologies for Biology and Medicine, 114570B (9 April 2020); https://doi.org/10.1117/12.2559615

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Intestine

Visualization

Angiography

Blood circulation

Coherence (optics)

Tissues

Blood vessels

Show All Keywords

Keywords/Phrases

Search In:

Publication Years