Photothermal therapy of tumors has become an important method. In recent years, the method has been widely studied in tumor therapy, and the corresponding results has been obtained well. However, it is still not been solved the effects of the heat on the tumor and its surrounding tissues, and the temperature control in corresponding tissues during the treatment process. In our study, the mouse skin was chosen as the research object. Infrared thermal imager and optical coherence tomography (OCT) were combined to monitor the photothermal therapy in real time in vivo. Temperature and morphological structure were obtained during the photothermal therapy process. The results will provide effective guidance for the photothermal therapy of tissue.
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