Simulation of clinical focal laser ablation treatments to create a dosimetry model of the ablation zone using critical CEM43 values

Luigi A. van Riel M.D.; Rob A. van Kollenburg M.D.; Remko Zweije; Hans Crezee; Theo M. de Reijke M.D.; Jorg R. Oddens M.D.; Ton G. van Leeuwen; Martijn de Bruin

doi:10.1117/12.2582697

5 March 2021 Simulation of clinical focal laser ablation treatments to create a dosimetry model of the ablation zone using critical CEM43 values

Luigi A. van Riel M.D., Rob A. van Kollenburg M.D., Remko Zweije, Hans Crezee, Theo M. de Reijke M.D., Jorg R. Oddens M.D., Ton G. van Leeuwen, Martijn de Bruin

Author Affiliations +

Proceedings Volume 11619, Advanced Photonics in Urology; 1161906 (2021) https://doi.org/10.1117/12.2582697
Event: SPIE BiOS, 2021, Online Only

Abstract

Transperineal laser ablation (TPLA) treatment of prostate cancer allows for a minimal invasive treatment approach. However, a predictive dosimetry model for accurate treatment planning for prostate cancer is not yet available. Therefore, we simulated TPLA treatments on porcine liver and quantitatively evaluated thermal distribution and histology slides were made. Hereby, we determined the cumulative equivalent thermal isoeffect dose at 43°C (CEM43) that predicts cell death and led to the development of a dosimetry model.

Conference Presentation

Citation Download Citation

Luigi A. van Riel M.D., Rob A. van Kollenburg M.D., Remko Zweije, Hans Crezee, Theo M. de Reijke M.D., Jorg R. Oddens M.D., Ton G. van Leeuwen, and Martijn de Bruin "Simulation of clinical focal laser ablation treatments to create a dosimetry model of the ablation zone using critical CEM43 values", Proc. SPIE 11619, Advanced Photonics in Urology, 1161906 (5 March 2021); https://doi.org/10.1117/12.2582697

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE