Evaluation of cutaneous pharmacokinetics: the past, the present and the future

Priyanka Ghosh; Sam G. Raney; Markham C. Luke

doi:10.1117/12.2576905

5 March 2021 Evaluation of cutaneous pharmacokinetics: the past, the present and the future

Priyanka Ghosh, Sam G. Raney, Markham C. Luke

Author Affiliations +

Proceedings Volume 11624, Visualizing and Quantifying Drug Distribution in Tissue V; 1162405 (2021) https://doi.org/10.1117/12.2576905
Event: SPIE BiOS, 2021, Online Only

Abstract

Being able to visualize and quantify where an active ingredient and/or excipient resides within a multiphasic formulation (e.g., a semisolid emulsion), how the drug diffuses and is released from the dosage form, and the delivery and disposition of the drug at the intended site of action can be a powerful tool the development of locally acting drug products such as a dermatological cream. The presentation will focus on how techniques for the evaluation of cutaneous pharmacokinetics have evolved over the years, and how noninvasive imaging-based techniques are being utilized to mechanistically understand drug availability and drug disposition following topical application.

Conference Presentation

Citation Download Citation

Priyanka Ghosh, Sam G. Raney, and Markham C. Luke "Evaluation of cutaneous pharmacokinetics: the past, the present and the future", Proc. SPIE 11624, Visualizing and Quantifying Drug Distribution in Tissue V, 1162405 (5 March 2021); https://doi.org/10.1117/12.2576905

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