Continuous wave diffuse correlation spectroscopy beyond the water peak enabled by InGaAs SPAD cross correlation

Mitchell B. Robinson; Stefan Carp; Adriano Peruch; Nisan Ozana; Maria Franceschini

doi:10.1117/12.2578914

5 March 2021 Continuous wave diffuse correlation spectroscopy beyond the water peak enabled by InGaAs SPAD cross correlation

Mitchell B. Robinson, Stefan Carp, Adriano Peruch, Nisan Ozana, Maria Franceschini

Author Affiliations +

Proceedings Volume 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics; 116291Q (2021) https://doi.org/10.1117/12.2578914
Event: SPIE BiOS, 2021, Online Only

Abstract

Diffuse correlation spectroscopy (DCS) is an established diffuse optical technique that uses the analysis of temporal speckle intensity fluctuations to measure blood flow in tissue. DCS cerebral blood flow measurements in clinical applications have shown promise, but measurements contain contamination of the signal from changes in superficial blood flow. Recent studies have shown that moving to wavelengths beyond the water absorption peak at 970 nm when making DCS measurements improves SNR and reduced influence of superficial flow. Here, we present a DCS system operating at 1064 nm utilizing two InGaAs SPADs to calculate the cross correlation to address detector non-idealities.

Conference Presentation

Citation Download Citation

Mitchell B. Robinson, Stefan Carp, Adriano Peruch, Nisan Ozana, and Maria Franceschini "Continuous wave diffuse correlation spectroscopy beyond the water peak enabled by InGaAs SPAD cross correlation", Proc. SPIE 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, 116291Q (5 March 2021); https://doi.org/10.1117/12.2578914

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