Understanding what happens in the brain during healthy ageing is important for several reasons ranging from its correlation to cognitive function to the research of neurodegenerative diseases and their biomarkers. In recent years, studies have linked certain biomarkers to both ageing and neurodegenerative diseases, but there is still more to be found and concluded. Inspired by current developments in machine learning, the use of artificial neural networks (ANN) as a method for extracting new informational biomarkers has been investigated. The brain consists of several functionally connected regions and can thus be modeled and analyzed using graph theory. ANNs and graph theory can be combined into graph neural networks, which when applied on human brain data have shown great promise. We aim to investigate the usage of GNNs on age-related data, in the search for biomarkers and other important features related to the ageing brain.
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