Spatial resolution improvement of acoustic resolution photoacoustic microscopy using cycle-consistent GAN

Thanh Dat Le; Changho Lee

doi:10.1117/12.2608112

3 March 2022 Spatial resolution improvement of acoustic resolution photoacoustic microscopy using cycle-consistent GAN

Thanh Dat Le, Changho Lee

Proceedings Volume 11960, Photons Plus Ultrasound: Imaging and Sensing 2022; 119600C (2022) https://doi.org/10.1117/12.2608112
Event: SPIE BiOS, 2022, San Francisco, California, United States

Conference Poster

Abstract

Photoacoustic microscopy (PAM) is a multiscale microscopy technique with optical absorption contrast. With tight acoustic focusing, acoustic-resolution (AR-PAM) reaches the depth of several centimeters in biological tissue, but the lateral resolution is relatively poorer than optical-resolution PAM (OR-PAM). We proposed using CycleGAN to generate new OR-PAM images from the original AR-PAM images. We prepared two AR & OR-PAM datasets from leaf phantom and mouse-ear samples. After completing the CycleGAN process, we estimated the quality comparison between the original AR-PAM and the generated OR-PAM images. Finally, the results showed the ability to obtain high spatial resolution PAM images without hardware updates.

Conference Presentation

Citation Download Citation

Thanh Dat Le and Changho Lee "Spatial resolution improvement of acoustic resolution photoacoustic microscopy using cycle-consistent GAN", Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119600C (3 March 2022); https://doi.org/10.1117/12.2608112

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