The applications of gold nanoparticles in drug delivery

Zechen Li; Yingqi Su; Haochen Zhang

doi:10.1117/12.2637359

10 June 2022 The applications of gold nanoparticles in drug delivery

Zechen Li, Yingqi Su, Haochen Zhang

Proceedings Volume 12179, Second International Conference on Medical Imaging and Additive Manufacturing (ICMIAM 2022); 121790Y (2022) https://doi.org/10.1117/12.2637359
Event: Second International Conference on Medical Imaging and Additive Manufacturing (ICMIAM 2022), 2022, Xiamen, China

Abstract

Nanoparticle play an important role in drug delivery system. Traditional drug delivery methods have too many hinders that can overcome by embellishing nanopaticle. For those advantage, nanoparticle application in drug delivery system as research interest in great demand. This paper overview gold nanoparticle used as in protein nanocarriers and used in nucleic acid delivery. Meanwhile use less length to introduce the mesoporous nanoparticle in drug delivery to offer another think about nanoparticle using in drug delivery. Protein expression disorder or dysfunctional protein production leads to disease state. Restoring biological function by supplementing protein is the safest, most direct and most effective way to treat diseases, but their therapeutic use is limited because they are vulnerable to endosomal internalization, instability and immunogenicity. Efficient and universal system based on gold nanoparticle DNA has characteristics similar to nanoblocks, allowing any recombinant protein to be loaded and transported to mammalian living systems without additional modification. And as report, nucleic acid can treat some genetic disease and cancer, gold nanoparticle can be a good tool to delivery nucleic acid. In addition, mesoporous nanoparticle also can help some drug delivery system to control their release.

Citation Download Citation

Zechen Li, Yingqi Su, and Haochen Zhang "The applications of gold nanoparticles in drug delivery", Proc. SPIE 12179, Second International Conference on Medical Imaging and Additive Manufacturing (ICMIAM 2022), 121790Y (10 June 2022); https://doi.org/10.1117/12.2637359

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