Iridotomy and capsulotomy on porcine eyes with ultrashort laser pulses in the picosecond regime

Michael Körber; Milan Fritsche; Andreas Giese; Konstantina Kostourou; Daniel Kopf; Manfred Kottcke; Francesco Luciani; Jonathan Wenk; Bernd Braun; Josef M. Schmidbauer

doi:10.1117/12.2650151

14 March 2023 Iridotomy and capsulotomy on porcine eyes with ultrashort laser pulses in the picosecond regime

Michael Körber, Milan Fritsche, Andreas Giese, Konstantina Kostourou, Daniel Kopf, Manfred Kottcke, Francesco Luciani, Jonathan Wenk, Bernd Braun, Josef M. Schmidbauer

Author Affiliations +

Proceedings Volume 12360, Ophthalmic Technologies XXXIII; 123600J (2023) https://doi.org/10.1117/12.2650151
Event: SPIE BiOS, 2023, San Francisco, California, United States

Conference Poster

Abstract

The laser systems currently used in ophthalmology either have some pulse length dependent side effects or are very expensive due to their complexity. Therefore, a newly developed approach using picosecond laser sources is investigated. These lasers combine the advantages of the low price of currently used short-pulse laser sources with the cold material ablation possibilities of high-end femtosecond sources. The surgeries intended are laser iridotomy, capsulotomy/post-cataract treatment and selective laser-trabeculoplasty (SLT). They are demonstrated on post mortem porcine eyes. The result is a more precise, less frayed tissue ablation with picosecond pulses in comparison to nanosecond pulses. The pulse energy could be reduced to (50 20) µJ per pulse instead of 1mJ to 10mJ per pulse, which is currently applied. The study of shock waves and cavitation bubbles revealed a huge difference in pressure between picosecond pulses (0:25MPa at 50 µJ) and nanosecond pulses (37MPa at 5 mJ). Therefore, the risk of collateral damage leading to potential additional clinical patterns and adverse effects could be significantly reduced.

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Michael Körber, Milan Fritsche, Andreas Giese, Konstantina Kostourou, Daniel Kopf, Manfred Kottcke, Francesco Luciani, Jonathan Wenk, Bernd Braun, and Josef M. Schmidbauer "Iridotomy and capsulotomy on porcine eyes with ultrashort laser pulses in the picosecond regime", Proc. SPIE 12360, Ophthalmic Technologies XXXIII, 123600J (14 March 2023); https://doi.org/10.1117/12.2650151

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