Lung nodule biopsy guided using a 30 MHz ultrasound transducer: in vitro study

Ben Kreager; Sunho Moon; Josh Mitchell; Huaiyu Wu; Chang Peng; Marie Muller; Chih-Chung Huang; Xiaoning Jiang

doi:10.1117/12.2658585

25 April 2023 Lung nodule biopsy guided using a 30 MHz ultrasound transducer: in vitro study

Ben Kreager, Sunho Moon, Josh Mitchell, Huaiyu Wu, Chang Peng, Marie Muller, Chih-Chung Huang, Xiaoning Jiang

Proceedings Volume 12488, Health Monitoring of Structural and Biological Systems XVII; 124881E (2023) https://doi.org/10.1117/12.2658585
Event: SPIE Smart Structures + Nondestructive Evaluation, 2023, Long Beach, California, United States

Abstract

Ultrasound is often favored in biopsy guidance since it is non-ionizing, inexpensive, portable, and has a high frame rate. However, imaging probes that operate at a low frequency may not be able to differentiate between tiny targets and surrounding tissues clearly, and at a high frequency, it suffers from tissue scattering and signals attenuation, which is hard to image deeper targets such as lung tissues. In this study, we developed a biopsy needle (with a size of 18 G) integrated with a 30 MHz high-frequency ultrasound transducer (axial resolution: ~ 100 µm) for the lung nodule biopsy in vitro test. To mimic contrasting biological tissues, a melamine foam-gelatin phantom was developed. With an advancing step of 0.5 mm, the distance from the biopsy needle to the gelatin-foam boundary was estimated by the speed of sound in gelatin and the time-of-flight of the echo signal. The results showed that the 30 MHz ultrasound transducer can map the geometry of the gelatin-foam boundary, indicating the capability of distinguishing tumor and healthy lung tissue with this ultrasound-guided biopsy technique.

Conference Presentation

Citation Download Citation

Ben Kreager, Sunho Moon, Josh Mitchell, Huaiyu Wu, Chang Peng, Marie Muller, Chih-Chung Huang, and Xiaoning Jiang "Lung nodule biopsy guided using a 30 MHz ultrasound transducer: in vitro study", Proc. SPIE 12488, Health Monitoring of Structural and Biological Systems XVII, 124881E (25 April 2023); https://doi.org/10.1117/12.2658585

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available