Laser procedures are very popular. But the effectiveness of most skin rejuvenation procedures has not been proven. Purpose: to determine the true picture of morphological processes occurring after exposure to laser radiation on the skin. Materials and methods: The work uses HiFU with a 75 MHz sensor, Er:glass laser. 15 patients aged 35 to 65 years were examined. For anesthesia numping cream with lidocaine 2.5% was used. Results: after application anesthesia, the signal intensity within the epidermis significantly decreases, which indicates the presence of signs of edema in this layer. Immediately after the procedure, pronounced signs of edema in the dermis were noted in 100% of cases. A month after the procedure, there was an increase in signal intensity within the dermis. Conclusions: As a result of laser exposure the changes manifest themselves in the production of collagen, and not in the formation of focal fibrous changes. The use of diagnostic methods will improve the effectiveness of procedures
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