Protection of COVID-19 vaccine in general and special population

Yan Zhuang

doi:10.1117/12.2691859

7 September 2023 Protection of COVID-19 vaccine in general and special population

Yan Zhuang

Proceedings Volume 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023); 127892Q (2023) https://doi.org/10.1117/12.2691859
Event: International Conference on Modern Medicine and Global Health (ICMMGH 2023), 2023, Oxford, United Kingdom

Abstract

As the continuous mutation of the COVID-19 virus increases the uncontrollability of the virus, it imposes a great social-economic burden on health care. It is crucial to select the best vaccines to accelerate herd immunity with minimal side effects. An essential role of immunization by vaccines is to trigger the production of antibodies in the body, while the effectiveness and protection of vaccines are determined by several factors and thus have drawn great research interest. So far, several approved COVID-19 vaccines have been applied globally, with different booster strategies. Therefore, comparing efficiency of vaccines and booster strategy are needed to offer higher protection, with particular interest for immune-insufficient population. The present study focuses on the comparison of monovalent and bivalent vaccines, as well as comparing different booster strategies, by reviewing clinical findings regarding each specific vaccines or booster strategies. In general, bivalent vaccines were more successful than monovalent vaccines for immunization, and heterologous vaccines were preferred than homologous vaccines for immunization against virus mutations. However, there are few vaccines that are approved for special populations due to safety concerns, such as children and pregnant women, which warrants further investigation to address this imperative issue. In addition, the potential higher effectiveness of heterologous vaccines indicates that it might provide better immunity for special populations, which requires more research attention.

Citation Download Citation

Yan Zhuang "Protection of COVID-19 vaccine in general and special population", Proc. SPIE 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023), 127892Q (7 September 2023); https://doi.org/10.1117/12.2691859

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KEYWORDS

Safety

Antibodies

COVID 19

Proteins

Analytical research

Clinical trials

Medicine

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