Stage III endobronchial squamous cell cancer: survival after Nd:YAG laser combined with photodynamic therapy versus Nd:YAG laser or photodynamic therapy alone

James S. McCaughan M.D.; Rostislav D. Barabash; Philip Hawley M.D.

doi:10.1117/12.44067

1 June 1991 Stage III endobronchial squamous cell cancer: survival after Nd:YAG laser combined with photodynamic therapy versus Nd:YAG laser or photodynamic therapy alone

James S. McCaughan M.D., Rostislav D. Barabash, Philip Hawley M.D.

Author Affiliations +

Proceedings Volume 1426, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques; (1991) https://doi.org/10.1117/12.44067
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Eighty-eight patients with stage III endobronchial squamous cell cancer were treated with Nd:YAG laser therapy alone (49), photodynamic therapy (PDT) alone (14), or a combination of Nd:YAG and PDT therapy (25). Mean survival rates were as follows: PDT equals 4.8 months, Nd:YAG therapy equals 3.3 months, PDT followed by Nd:YAG equals 10.9 months, Nd:YAG followed by PDT equals 9.0 months, and all combination therapy equals 9.2 months. The difference between survival rates for combination therapy and Nd:YAG only was statistically significant (P equals 0.003). The authors recommend a combination of PDT and Nd:YAG laser therapies in patients who have undergone or are not amenable to conventional therapies for this tumor. Further, the authors recommend that these patients be treated early, before the tumor spreads to other bronchi or becomes large and bloody, in order to reduce the risk for perioperative complications.

Citation Download Citation

James S. McCaughan M.D., Rostislav D. Barabash, and Philip Hawley M.D. "Stage III endobronchial squamous cell cancer: survival after Nd:YAG laser combined with photodynamic therapy versus Nd:YAG laser or photodynamic therapy alone", Proc. SPIE 1426, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, (1 June 1991); https://doi.org/10.1117/12.44067

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available