Spectroscopy in pharmaceutical development: an overview

Stephen Scypinski; Ramaswamy Murari; Anne Grant; Sammy Ng

doi:10.1117/12.137725

14 August 1992 Spectroscopy in pharmaceutical development: an overview

Stephen Scypinski, Ramaswamy Murari, Anne Grant, Sammy Ng

Proceedings Volume 1681, Optically Based Methods for Process Analysis; (1992) https://doi.org/10.1117/12.137725
Event: SPIE's 1992 Symposium on Process Control and Monitoring, 1992, Somerset, NJ, United States

Abstract

Spectroscopic techniques play a key role in the everyday work of the pharmaceutical analyst. In addition to the normal use of the various spectroscopies for simple, routine analyses, a pharmaceutical analytical chemist might use spectroscopy to perform a host of additional functions. These might include, for example, the characterization of a polymorphic substance by either X-ray diffraction or nuclear magnetic resonance spectroscopy, the identification of a foreign material in a tablet dosage form by infrared microspectroscopy, or the selection of a wavelength for liquid chromatographic analysis by photodiode array ultraviolet-visible spectroscopy. The following presentation is meant to acquaint the non-pharmaceutical chemist with some of the ways spectroscopy is utilized in the pharmaceutical analysis research and development laboratory.

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Stephen Scypinski, Ramaswamy Murari, Anne Grant, and Sammy Ng "Spectroscopy in pharmaceutical development: an overview", Proc. SPIE 1681, Optically Based Methods for Process Analysis, (14 August 1992); https://doi.org/10.1117/12.137725

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