Molecular charge mapping with electrostatic force microscope

Yaojian Leng; Clayton C. Williams

doi:10.1117/12.146383

4 June 1993 Molecular charge mapping with electrostatic force microscope

Yaojian Leng, Clayton C. Williams

Proceedings Volume 1855, Scanning Probe Microscopies II; (1993) https://doi.org/10.1117/12.146383
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

We are attempting charge mapping and potentiometry on biological and molecular systems using a modified Atomic Force Microscope (AFM)--Electrostatic Force Microscope (EFM). With an interferometric detection system, we have obtained potentiometric sensitivity better than 0.1 mV and spatial resolution of about 200 angstroms. The images of red blood cells in air clearly show surface potential variation, independent of topography. We imaged FEP ((poly)tetrafluororethylene -co- hexafluoropropylene) films lithographically patterned with APS (poly(aminopropyl)siloxane). We have been able to positively identify the modified regions (APS) from the unmodified regions (FEP) using charge information. The charge density we estimated on the unmodified FEP regions of our samples is about 10^-9C/cm².

Citation Download Citation

Yaojian Leng and Clayton C. Williams "Molecular charge mapping with electrostatic force microscope", Proc. SPIE 1855, Scanning Probe Microscopies II, (4 June 1993); https://doi.org/10.1117/12.146383

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available