Holmium:YAG laser angioplasty: treatment of acute myocardial infarction

On Topaz M.D.

doi:10.1117/12.146568

23 June 1993 Holmium:YAG laser angioplasty: treatment of acute myocardial infarction

On Topaz M.D.

Proceedings Volume 1878, Diagnostic and Therapeutic Cardiovascular Interventions III; (1993) https://doi.org/10.1117/12.146568
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

We report our clinical experience with a group of 14 patients who presented with acute myocardial infarction. A holmium:YAG laser was applied to the infarct-related artery. This laser emits 250 - 600 mJ per pulse, with a pulse length of 250 microseconds and repetition rate of 5 Hz. Potential benefits of acute thrombolysis by lasers include the absence of systemic lytic state; a shortened thrombus clearing time relative to using thrombolytics; safe removal of the intracoronary thrombus and facilitation of adjunct balloon angioplasty. Potential clinical difficulties include targeting the obstructive clot and plaque, creation of debris and distal emboli and laser-tissue damage. It is conceivable that holmium:YAG laser can be a successful thrombolytic device as its wave length (2.1 microns) coincides with strong water absorption peaks. Since it is common to find an atherosclerotic plaque located under or distal to the thrombotic occlusion, this laser can also be applied for plaque ablation, and the patient presenting with acute myocardial infarction can clearly benefit from the combined function of this laser system.

Citation Download Citation

On Topaz M.D. "Holmium:YAG laser angioplasty: treatment of acute myocardial infarction", Proc. SPIE 1878, Diagnostic and Therapeutic Cardiovascular Interventions III, (23 June 1993); https://doi.org/10.1117/12.146568

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