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Four lesions of early carcinoma of the esophagus found during endoscopic biopsies in three patients were treated with photodynamic therapy. Follow-up biopsies over 9 - 24 months remain negative for carcinoma. Endoscopic ultrasonography is essential for proper staging and treatment planning for these patients. Photodynamic therapy may provide an alternative to surgical resection for early esophageal carcinoma or severe dysplasia in Barrett's esophagus.
Bergein F. Overholt M.D.,Masoud Panjehpour,Elmeria Teffeteller, andS. Mark Rose
"Photodynamic therapy (PDT) utilizing PhotofrinR for treatment of early esophageal cancer", Proc. SPIE 1881, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II, (18 June 1993); https://doi.org/10.1117/12.146328
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Bergein F. Overholt M.D., Masoud Panjehpour, Elmeria Teffeteller, S. Mark Rose, "Photodynamic therapy (PDT) utilizing PhotofrinR for treatment of early esophageal cancer," Proc. SPIE 1881, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy II, (18 June 1993); https://doi.org/10.1117/12.146328