Lanthanide macrocyclic complexes, 'quantum dyes': optical properties and significance

Lidia M. Vallarino; Patrick M. Harlow; Robert C. Leif

doi:10.1117/12.144724

18 May 1993 Lanthanide macrocyclic complexes, 'quantum dyes': optical properties and significance

Lidia M. Vallarino, Patrick M. Harlow, Robert C. Leif

Author Affiliations +

Proceedings Volume 1885, Advances in Fluorescence Sensing Technology; (1993) https://doi.org/10.1117/12.144724
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

Macrocylic complexes of the lanthanide (III) ions were functionalized to permit their attachment to antibodies, nucleic acid probes, and any other species capable of specific binding. The Eu(III) complex was found to possess a combination of properties (water solubility, inertness to metal release, ligand-sensitized luminescence, reactive peripheral functionalities) that make it suitable as a luminescent marker for bio-substrates. Its coupling to avidin was achieved, and the properties of the resulting conjugate were investigated.

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Lidia M. Vallarino, Patrick M. Harlow, and Robert C. Leif "Lanthanide macrocyclic complexes, 'quantum dyes': optical properties and significance", Proc. SPIE 1885, Advances in Fluorescence Sensing Technology, (18 May 1993); https://doi.org/10.1117/12.144724

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