NMR measurements of intracellular ions in hypertension

Joseph C. Veniero; R. K. Gupta

doi:10.1117/12.151171

27 August 1993 NMR measurements of intracellular ions in hypertension

Joseph C. Veniero, R. K. Gupta

Proceedings Volume 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods; (1993) https://doi.org/10.1117/12.151171
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

The NMR methods for the measurement of intracellular free Na⁺, K⁺, Mg²⁺, Ca²⁺, and H⁺ are introduced. The recent literature is then presented showing applications of these methods to cells and tissues from hypertensive animal model systems, and humans with essential hypertension. The results support the hypothesis of consistent derangement of the intracellular ionic environment in hypertension. The theory that this derangement may be a common link in the disease states of high blood pressure and abnormal insulin and glucose metabolism, which are often associated clinically, is discussed.

Citation Download Citation

Joseph C. Veniero and R. K. Gupta "NMR measurements of intracellular ions in hypertension", Proc. SPIE 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods, (27 August 1993); https://doi.org/10.1117/12.151171

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