Fluorescence mapping of transmembrane potentials during cardiac stimulation

Stephen B. Knisley; Bruce C. Hill

doi:10.1117/12.176581

26 May 1994 Fluorescence mapping of transmembrane potentials during cardiac stimulation

Stephen B. Knisley, Bruce C. Hill

Proceedings Volume 2132, Clinical Applications of Modern Imaging Technology II; (1994) https://doi.org/10.1117/12.176581
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

An important effect of electrical stimulation on myocardial tissue is the change in the transmembrane voltage induced during the stimulation pulse. This initial effect then activates transmembrane voltage-dependent ion channels and can produce a propagated action potential after the pulse. Fluorescence mapping with transmembrane voltage-sensitive dye has been used to measure the direction of the initial change in transmembrane voltage-sensitive during a stimulation pulse and the magnitude of the change relative to the action potential amplitude.

Citation Download Citation

Stephen B. Knisley and Bruce C. Hill "Fluorescence mapping of transmembrane potentials during cardiac stimulation", Proc. SPIE 2132, Clinical Applications of Modern Imaging Technology II, (26 May 1994); https://doi.org/10.1117/12.176581

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