Epidermal heating during laser-induced photothermolysis of port wine stains: modeling melanosomal heating after dynamic cooling of the skin surface

Lars Othar Svaasand; Thomas E. Milner; Bahman Anvari; Lill Tove Norvang Nilsen; B. Samuel Tanenbaum; Sol Kimel; Michael W. Berns; J. Stuart Nelson M.D.

doi:10.1117/12.199218

18 January 1995 Epidermal heating during laser-induced photothermolysis of port wine stains: modeling melanosomal heating after dynamic cooling of the skin surface

Lars Othar Svaasand, Thomas E. Milner, Bahman Anvari, Lill Tove Norvang Nilsen, B. Samuel Tanenbaum, Sol Kimel, Michael W. Berns, J. Stuart Nelson M.D.

Author Affiliations +

Proceedings Volume 2323, Laser Interaction with Hard and Soft Tissue II; (1995) https://doi.org/10.1117/12.199218
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

The clinical objective in treatment of port wine stains is to maximize thermal damage to the abnormal blood vessels without introducing thermal damage to the normal overlying epidermis. The rationale of dynamic cooling is to protect the epidermis from thermal damage by selectively cooling this layer down immediately before delivering the laser pulse. This work discusses the thermal dynamics of epidermal cooling by milliseconds cryogen spurts and melanosomal heating by the laser pulse.

Citation Download Citation

Lars Othar Svaasand, Thomas E. Milner, Bahman Anvari, Lill Tove Norvang Nilsen, B. Samuel Tanenbaum, Sol Kimel, Michael W. Berns, and J. Stuart Nelson M.D. "Epidermal heating during laser-induced photothermolysis of port wine stains: modeling melanosomal heating after dynamic cooling of the skin surface", Proc. SPIE 2323, Laser Interaction with Hard and Soft Tissue II, (18 January 1995); https://doi.org/10.1117/12.199218

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