Self-assembled and supported BLMs as an adaptive material for biotechnology

Angelica L. Ottova-Leitmannova; Vladimir Tvarozek; T. Hianik; Tiean Zhou; W. Ziegler; H. Ti Tien

doi:10.1117/12.232135

9 February 1996 Self-assembled and supported BLMs as an adaptive material for biotechnology

Angelica L. Ottova-Leitmannova, Vladimir Tvarozek, T. Hianik, Tiean Zhou, W. Ziegler, H. Ti Tien

Proceedings Volume 2716, Smart Structures and Materials 1996: Smart Materials Technologies and Biomimetics; (1996) https://doi.org/10.1117/12.232135
Event: 1996 Symposium on Smart Structures and Materials, 1996, San Diego, CA, United States

Abstract

Cell membranes play a vital role in energy conversion, information processing and signal transduction. This is owing to the fact that most physiological activities involve lipid bilayer- based receptor-ligand interactions. Some of the outstanding examples are ATP synthesis, ion transport, antigen-antibody binding, and gated channels. One approach to study these interactions in vitro is facilitated by employing artificial BLMs (bilayer lipid membranes). Our current efforts have been focused on ion and/or molecular selectivity and specificity using recently available self-assembled BLMs on solid support (i.e. s-BLMs) which, with their enhanced stability, greatly aid in research areas of membrane biochemistry, biophysics, and cell biology as well as in biosensor designs and molecular devices development. In this report, our recent work along with the experiments done in collaboration with others on s-BLMs are presented.

Citation Download Citation

Angelica L. Ottova-Leitmannova, Vladimir Tvarozek, T. Hianik, Tiean Zhou, W. Ziegler, and H. Ti Tien "Self-assembled and supported BLMs as an adaptive material for biotechnology", Proc. SPIE 2716, Smart Structures and Materials 1996: Smart Materials Technologies and Biomimetics, (9 February 1996); https://doi.org/10.1117/12.232135

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