Endoscopic fluorescence imaging for early assessment of anastomotic recurrence of Crohn's disease

Serge R. Mordon; Vincent Maunoury M.D.; K. Geboes; Olivier Klein; P. Desreumaux; A. Debaert; Jean-Frederic Colombel

doi:10.1117/12.339191

12 February 1999 Endoscopic fluorescence imaging for early assessment of anastomotic recurrence of Crohn's disease

Serge R. Mordon, Vincent Maunoury M.D., K. Geboes, Olivier Klein, P. Desreumaux, A. Debaert, Jean-Frederic Colombel

Proceedings Volume 3567, Optical and Imaging Techniques for Biomonitoring IV; (1999) https://doi.org/10.1117/12.339191
Event: BiOS Europe '98, 1998, Stockholm, Sweden

Abstract

Crohn's disease is an inflammatory bowel disease of unknown etiology. The mechanism of the initial mucosal alterations is still unclear: ulcerations overlying lymphoid follicles and/or vasculitis have been proposed as the early lesions. We have developed a new and original method combining endoscopy of fluorescence angiography for identifying the early pathological lesions, occurring in the neo-terminal ileum after right ileocolonic resection. The patient population consisted of 10 subjects enrolled in a prospective protocol of endoscopic follow-up at 3 and 12 months after surgery. Fluorescence imaging showed small spots giving a bright fluorescence distributed singly in mucosa which appeared normal in routine endoscopy. Histopathological examination demonstrated that the fluorescence of small spots originated from small, usually superficial, erosive lesions. In several cases, these erosive lesions occurred over lymphoid follicles. Endoscopic fluorescence imaging provides a suitable means of investigating the initial aspect of the Crohn's disease process in displaying some correlative findings between fluorescent aspects and early pathological mucosal alterations.

Citation Download Citation

Serge R. Mordon, Vincent Maunoury M.D., K. Geboes, Olivier Klein, P. Desreumaux, A. Debaert, and Jean-Frederic Colombel "Endoscopic fluorescence imaging for early assessment of anastomotic recurrence of Crohn's disease", Proc. SPIE 3567, Optical and Imaging Techniques for Biomonitoring IV, (12 February 1999); https://doi.org/10.1117/12.339191

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Luminescence

Endoscopy

Lymphatic system

Biopsy

Angiography

Colon

Inflammation

Show All Keywords

Keywords/Phrases

Search In:

Publication Years