Multichannel arrays on polymer substrates: toward a disposable proteomics chip

Holger Becker; Wolfgang Ehrfeld; Rainer Pommersheim

doi:10.1117/12.341266

10 March 1999 Multichannel arrays on polymer substrates: toward a disposable proteomics chip

Holger Becker, Wolfgang Ehrfeld, Rainer Pommersheim

Proceedings Volume 3680, Design, Test, and Microfabrication of MEMS and MOEMS; (1999) https://doi.org/10.1117/12.341266
Event: Design, Test, and Microfabrication of MEMS/MOEMS, 1999, Paris, France

Abstract

Miniaturization is dramatically changing the shape of biotechnology. After the first wave of discoveries inventions in the field of analytical methods and DNA-probes on silicon chips, the trend in recent years has been to more complex and integrated systems in terms of microfabrication for production purposes mainly focused on polymer substrates. Additionally, an increased complexity in the biochemical functionality for tasks like cell handling, cell lysis, polymerase chain reaction, DNA-sequencing and recently in the field of proteomics research can be observed. In this paper we describe the practical approach to a polymer substrate based, microfabricated chip-based multichannel array for 2D capillary electrophoresis. This chip can be fabricated by classical mass production techniques like hot embossing or injection modeling, and has the potential for on-chip-integration of electrodes and detection system.

Citation Download Citation

Holger Becker, Wolfgang Ehrfeld, and Rainer Pommersheim "Multichannel arrays on polymer substrates: toward a disposable proteomics chip", Proc. SPIE 3680, Design, Test, and Microfabrication of MEMS and MOEMS, (10 March 1999); https://doi.org/10.1117/12.341266

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