Enzyme catalyzed biochemical production in a polydimethylsiloxane microreactor

Cynthia K. Dickey; Bill B. Elmore; Francis Jones

doi:10.1117/12.395672

18 August 2000 Enzyme catalyzed biochemical production in a polydimethylsiloxane microreactor

Cynthia K. Dickey, Bill B. Elmore, Francis Jones

Proceedings Volume 4177, Microfluidic Devices and Systems III; (2000) https://doi.org/10.1117/12.395672
Event: Micromachining and Microfabrication, 2000, Santa Clara, CA, United States

Abstract

Study of an aqueous-phase reaction in an enzyme- catalyzedpolydimethylsiloxane (PDMS) microreactor is underway. In the present work, urease - an enzyme that catalyzes urea to ammonia and carbon dioxide has been immobilized within open microchannels of 450 micrometers (micrometers ) in diameter or less. Microchannels are templated within PDMS. Preliminary results demonstrate the proof of concept for conversion biochemicals via a PDMS-based microreactor system.

Citation Download Citation

Cynthia K. Dickey, Bill B. Elmore, and Francis Jones "Enzyme catalyzed biochemical production in a polydimethylsiloxane microreactor", Proc. SPIE 4177, Microfluidic Devices and Systems III, (18 August 2000); https://doi.org/10.1117/12.395672

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