Handheld advanced nucleic acid analyzer

William J. Benett; James B. Richards; Paul Stratton; Dean R. Hadley; Brian H. Bodtker; Shanavaz L. Nasarabadi; Fred P. Milanovich; Raymond P. Mariella Jr.; Ronald P. Koopman; Philip Belgrader

doi:10.1117/12.411712

29 December 2000 Handheld advanced nucleic acid analyzer

William J. Benett, James B. Richards, Paul Stratton, Dean R. Hadley, Brian H. Bodtker, Shanavaz L. Nasarabadi, Fred P. Milanovich, Raymond P. Mariella Jr., Ronald P. Koopman, Philip Belgrader

Author Affiliations +

Proceedings Volume 4200, Biochemical and Biomolecular Sensing; (2000) https://doi.org/10.1117/12.411712
Event: Environmental and Industrial Sensing, 2000, Boston, MA, United States

Abstract

There is a growing need for portable, lightweight, battery operated instruments capable of detecting and identifying bio-warfare and bio-terrorism agents in the field. To address this need, we have developed a handheld PCR instrument. LLNLs advanced thermal cycling technology and expertise with portable, field tested biological instrumentation, combined with the development of real-time, fluorescence based PCR assays, has enabled the development of a very portable, versatile, power efficient PCR instrument with a simplified operating system designed for use by first responders. The heart of the instrument is the sample module, which incorporates the advanced silicon thermal cycler developed at LLNL.

Citation Download Citation

William J. Benett, James B. Richards, Paul Stratton, Dean R. Hadley, Brian H. Bodtker, Shanavaz L. Nasarabadi, Fred P. Milanovich, Raymond P. Mariella Jr., Ronald P. Koopman, and Philip Belgrader "Handheld advanced nucleic acid analyzer", Proc. SPIE 4200, Biochemical and Biomolecular Sensing, (29 December 2000); https://doi.org/10.1117/12.411712

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