Material properties of engineered tissues evaluated with nondestructive methods

Monica T. Hinds; Sean J. Kirkpatrick; Donald Dean Duncan

doi:10.1117/12.472534

27 June 2002 Material properties of engineered tissues evaluated with nondestructive methods

Monica T. Hinds, Sean J. Kirkpatrick, Donald Dean Duncan

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Proceedings Volume 4617, Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical; (2002) https://doi.org/10.1117/12.472534
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

The rapidly advancing field of tissue engineering requires innovative approaches to characterize the changing properties of engineered constructs. Nondestructive evaluations of mechanical properties are a critical portion of this. Tissue engineers must have the ability to dynamically evaluate the growth of cells on material scaffolds producing engineered tissues. We have developed an acoustic method to stress the surface of tissues, and using optical techniques we are able to noninvasively measure the properties of the tissue. This method is compared to traditional uniaxial tensile mechanical testing. This new methodology provides a minimally invasive technique to strain tissues and noninvasively measure the mechanical properties of the material.

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Monica T. Hinds, Sean J. Kirkpatrick, and Donald Dean Duncan "Material properties of engineered tissues evaluated with nondestructive methods", Proc. SPIE 4617, Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, (27 June 2002); https://doi.org/10.1117/12.472534

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KEYWORDS

Tissues

Speckle

Collagen

Nondestructive evaluation

Proteins

Natural surfaces

Acoustics

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