Protein noises

Benjamin H. McMahon; Paul W. Fenimore; Montiago X. LaBute

doi:10.1117/12.497137

30 April 2003 Protein noises

Benjamin H. McMahon, Paul W. Fenimore, Montiago X. LaBute

Proceedings Volume 5110, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems; (2003) https://doi.org/10.1117/12.497137
Event: SPIE's First International Symposium on Fluctuations and Noise, 2003, Santa Fe, New Mexico, United States

Abstract

Diagrams of cellular processes present a clean, deterministic view of how biomolecules regulate the processes of life. Attempts to construct reaction networks which are true to the microscopic complexity of the system are intractable when only a few proteins are included. We argue here that several layers of microscopic modeling are needed to characterize the fluctuations, or noise, of biochemical systems and that this is necessary to develop predictive models of cellular processes. Our arguments are illustrated with the specific examples of myoglobin and protein kinases.

Citation Download Citation

Benjamin H. McMahon, Paul W. Fenimore, and Montiago X. LaBute "Protein noises", Proc. SPIE 5110, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems, (30 April 2003); https://doi.org/10.1117/12.497137

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available