Nonlinear optical spectroscopy of collagen transformation

V. Shcheslavskiy; Georgi I. Petrov; Solomon M. Saltiel; A. Boyko; V. Y. Petrussevich; Y. M. Petrussevich; Galina P. Petrova; Vladislav V. Yakovlev

doi:10.1117/12.531634

21 June 2004 Nonlinear optical spectroscopy of collagen transformation

V. Shcheslavskiy, Georgi I. Petrov, Solomon M. Saltiel, A. Boyko, V. Y. Petrussevich, Y. M. Petrussevich, Galina P. Petrova, Vladislav V. Yakovlev

Author Affiliations +

Proceedings Volume 5323, Multiphoton Microscopy in the Biomedical Sciences IV; (2004) https://doi.org/10.1117/12.531634
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

We report on the novel application of nonlinear optics to study molecular assemblies. By using the third-harmonic generation in solution we were able to determine both the third-order nonlinear susceptibility of collagen and the size of fibrils. The developed approach also helped us in revealing the helix-coil transformation of collagen in solution.

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V. Shcheslavskiy, Georgi I. Petrov, Solomon M. Saltiel, A. Boyko, V. Y. Petrussevich, Y. M. Petrussevich, Galina P. Petrova, and Vladislav V. Yakovlev "Nonlinear optical spectroscopy of collagen transformation", Proc. SPIE 5323, Multiphoton Microscopy in the Biomedical Sciences IV, (21 June 2004); https://doi.org/10.1117/12.531634

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