Structurally integrated organic light-emitting device (OLED)-based multianalyte sensing through analyte-oxidase interactions

Ruth Shinar; Chengliang Qian; Yuankun Cai; Zhaoqun Zhou; Bhaskar Choudhury; Joseph Shinar

doi:10.1117/12.629699

11 November 2005 Structurally integrated organic light-emitting device (OLED)-based multianalyte sensing through analyte-oxidase interactions

Ruth Shinar, Chengliang Qian, Yuankun Cai, Zhaoqun Zhou, Bhaskar Choudhury, Joseph Shinar

Author Affiliations +

Proceedings Volume 6007, Smart Medical and Biomedical Sensor Technology III; 600710 (2005) https://doi.org/10.1117/12.629699
Event: Optics East 2005, 2005, Boston, MA, United States

Abstract

The development of a compact structurally integrated platform for detection of multianalytes that consume oxygen in the presence of specific oxidase enzymes is described. The detection is based on monitoring the photoluminescence (PL) intensity or lifetime of a sensing element based on the oxygen sensitive dye Pt octaethyl porphyrin (PtOEP). The excitation source for the PL is an array of individually addressable green OLED pixels. The analytes are gas- phase and dissolved oxygen, glucose, lactate, and alcohol. The sensing element for each analyte includes a layer of PtOEP-doped polystyrene, whose PL lifetime decreases with increasing O₂ level, and a film or solution containing the oxidase enzyme specific to the analyte. Each sensing element is associated with two addressable ~2x2 mm² OLED pixels. The operation and performance metrics of the sensor under various conditions are described and discussed.

Citation Download Citation

Ruth Shinar, Chengliang Qian, Yuankun Cai, Zhaoqun Zhou, Bhaskar Choudhury, and Joseph Shinar "Structurally integrated organic light-emitting device (OLED)-based multianalyte sensing through analyte-oxidase interactions", Proc. SPIE 6007, Smart Medical and Biomedical Sensor Technology III, 600710 (11 November 2005); https://doi.org/10.1117/12.629699

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