Nanosensing applications of In<sub>2</sub>O<sub>3</sub> nanowires and carbon nanotubes

Chongwu Zhou; Chao Li; Marco Curreli; Henry Lin; Fumiaki N. Ishikawa; Ram Datar; Richard J. Cote; Mark E. Thompson

doi:10.1117/12.631077

17 November 2005 Nanosensing applications of In₂O₃ nanowires and carbon nanotubes

Chongwu Zhou, Chao Li, Marco Curreli, Henry Lin, Fumiaki N. Ishikawa, Ram Datar, Richard J. Cote, Mark E. Thompson

Proceedings Volume 6008, Nanosensing: Materials and Devices II; 60080F (2005) https://doi.org/10.1117/12.631077
Event: Optics East 2005, 2005, Boston, MA, United States

Abstract

We report complementary detection of prostate-specific antigen (PSA) using n-type In₂O₃ nanowires and p-type carbon nanotubes. Our innovation involves developing an approach to covalently attach antibodies to In₂O₃ NW surfaces via the onsite surface synthesis of phosphoric acid-succinylimide ester. Electronic measurements under dry conditions revealed complementary response for In₂O₃ NW and SWNT devices after the binding of PSA. Real time detection in solution has also been demonstrated for PSA down to 5 ng/mL, a benchmark concentration significant for clinical diagnosis of prostate cancer, which is the most frequently diagnosed cancer.

Citation Download Citation

Chongwu Zhou, Chao Li, Marco Curreli, Henry Lin, Fumiaki N. Ishikawa, Ram Datar, Richard J. Cote, and Mark E. Thompson "Nanosensing applications of In₂O₃ nanowires and carbon nanotubes", Proc. SPIE 6008, Nanosensing: Materials and Devices II, 60080F (17 November 2005); https://doi.org/10.1117/12.631077

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