A first demonstration of audio-frequency optical coherence elastography of tissue

Steven G. Adie; Sergey A. Alexandrov; Julian J. Armstrong; Brendan F. Kennedy; David D. Sampson

doi:10.1117/12.816210

30 December 2008 A first demonstration of audio-frequency optical coherence elastography of tissue

Steven G. Adie, Sergey A. Alexandrov, Julian J. Armstrong, Brendan F. Kennedy, David D. Sampson

Author Affiliations +

Proceedings Volume 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics; 71390U (2008) https://doi.org/10.1117/12.816210
Event: 1st Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics, 2008, Canterbury, United Kingdom

Abstract

Optical elastography is aimed at using the visco-elastic properties of soft tissue as a contrast mechanism, and could be particularly suitable for high-resolution differentiation of tumour from surrounding normal tissue. We present a new approach to measure the effect of an applied stimulus in the kilohertz frequency range that is based on optical coherence tomography. We describe the approach and present the first in vivo optical coherence elastography measurements in human skin at audio excitation frequencies.

Citation Download Citation

Steven G. Adie, Sergey A. Alexandrov, Julian J. Armstrong, Brendan F. Kennedy, and David D. Sampson "A first demonstration of audio-frequency optical coherence elastography of tissue", Proc. SPIE 7139, 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics, 71390U (30 December 2008); https://doi.org/10.1117/12.816210

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