Use of quantum dot-labeled imprinted polymer microparticles for detection of nitroaromatic compounds

R. Cody Stringer; Shubhra Gangopadhyay; Sheila A. Grant

doi:10.1117/12.852913

23 April 2010 Use of quantum dot-labeled imprinted polymer microparticles for detection of nitroaromatic compounds

R. Cody Stringer, Shubhra Gangopadhyay, Sheila A. Grant

Author Affiliations +

Proceedings Volume 7673, Advanced Environmental, Chemical, and Biological Sensing Technologies VII; 767304 (2010) https://doi.org/10.1117/12.852913
Event: SPIE Defense, Security, and Sensing, 2010, Orlando, Florida, United States

Abstract

The ability to detect high explosive compounds is a fundamental step in achieving the goal of creating devices capable of 'sniffing' out explosive devices. To detect high explosive compounds such as 2,4,6-trinitrotoluene (TNT), a molecularly imprinted polymer (MIP) sensor was developed. This sensor consists of MIP microspheres prepared using methacrylic acid as the functional monomer in a precipitation polymerization reaction. The MIP microspheres are then combined with fluorescent semiconductor nanocrystals, or quantum dots, via a simple crosslinking procedure. To study the sensor's ability to detect nitroaromatic analytes, the fluorescent-labeled MIP particles were exposed to aqueous 2,4- dinitrotoluene (DNT), a nitroaromatic molecule very similar to TNT. Characterization of the MIP particles shows a uniform size distribution, with an average diameter of approximately 615 nm. Imaging of the particles also shows that spherical shapes are being produced by the precipitation polymerization reaction. Preliminary data indicate that the sensor is capable of detecting nitroaromatic compounds in an aqueous solution. These results illustrate the future application of the fluorescent-labeled MIP sensor for detecting high explosives, with the potential for use in detecting vapors from explosive devices and in an array of environmental conditions.

Citation Download Citation

R. Cody Stringer, Shubhra Gangopadhyay, and Sheila A. Grant "Use of quantum dot-labeled imprinted polymer microparticles for detection of nitroaromatic compounds", Proc. SPIE 7673, Advanced Environmental, Chemical, and Biological Sensing Technologies VII, 767304 (23 April 2010); https://doi.org/10.1117/12.852913

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE