M. A. Vilensky,1 D. N. Agafonov,1 P. A. Timoshina,1 O. V. Shipovskaya,1 D. A. Zimnyakov,2,3 V. V. Tuchinhttps://orcid.org/0000-0001-7479-2694,1,3 P. A. Novikov1
1Saratov State Univ. (Russian Federation) 2Saratov State Technical Univ. (Russian Federation) 3Institute of Precision Mechanics and Control (Russian Federation)
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The results of experimental study of monitoring the microcirculation in tissue superficial layers of the internal organs at
gastro-duodenal hemorrhage with the use of laser speckles contrast analysis technique are presented. The
microcirculation monitoring was provided in the course of the laparotomy of rat abdominal cavity in the real time.
Microscopic hemodynamics was analyzed for small intestine and stomach under different conditions (normal state,
provoked ischemia, administration of vasodilative agents such as papaverine, lidocaine). The prospects and problems of
internal monitoring of micro-vascular flow in clinical conditions are discussed.
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M. A. Vilensky, D. N. Agafonov, P. A. Timoshina, O. V. Shipovskaya, D. A. Zimnyakov, V. V. Tuchin, P. A. Novikov, "Full-field speckle correlation technique as applied to blood flow monitoring," Proc. SPIE 7898, Dynamics and Fluctuations in Biomedical Photonics VIII, 78981C (3 March 2011); https://doi.org/10.1117/12.879890