Wavelength multiplexing for FD-OCT speckle averaging

Gijs van Soest; Evelyn Regar; Brett E. Bouma; Guillermo J. Tearney; Antonius F. W. van der Steen

doi:10.1117/12.906335

9 February 2012 Wavelength multiplexing for FD-OCT speckle averaging

Gijs van Soest, Evelyn Regar, Brett E. Bouma, Guillermo J. Tearney, Antonius F. W. van der Steen

Author Affiliations +

Proceedings Volume 8207, Photonic Therapeutics and Diagnostics VIII; 820742 (2012) https://doi.org/10.1117/12.906335
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.

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Gijs van Soest, Evelyn Regar, Brett E. Bouma, Guillermo J. Tearney, and Antonius F. W. van der Steen "Wavelength multiplexing for FD-OCT speckle averaging", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 820742 (9 February 2012); https://doi.org/10.1117/12.906335

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KEYWORDS

Speckle

Optical coherence tomography

Signal attenuation

Multiplexing

Tissue optics

Image resolution

Image processing

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