Paper
15 October 2013 A novel bio-detecting chip based on the opened fiber surface plasmon enhancement mechanism
Author Affiliations +
Proceedings Volume 8924, Fourth Asia Pacific Optical Sensors Conference; 892420 (2013) https://doi.org/10.1117/12.2031689
Event: Asia Pacific Optical Sensors Conference 2013, 2013, Wuhan, China
Abstract
A novel bio-detecting chip configuration based on the fiber surface plasmon enhancement mechanism is proposed and analyzed. Our improvement is proposing to couple the specialized shell-isolated gold nanoparticles into the sensing region of the opened fiber-integrated microfluidic chip, and achieving drastic surface plasmon enhancement by employing the guided optical mode. Simulation shows that the optical intensity distribution near the surface of exposed fiber hole is enhanced drastically, which could be beneficial to the fluorescence or Raman enhancement. Our work could contribute to searching novel microfluidic chip based bio-detecting methods such as for tracing poisonous and harmful substances detection.
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Guanjun Wang, Yiping Wang, Changrui Liao, and Jiangtao Zhou "A novel bio-detecting chip based on the opened fiber surface plasmon enhancement mechanism", Proc. SPIE 8924, Fourth Asia Pacific Optical Sensors Conference, 892420 (15 October 2013); https://doi.org/10.1117/12.2031689
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KEYWORDS
Surface plasmons

Luminescence

Microfluidics

Gold

Nanoparticles

Raman spectroscopy

Biological research

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