A comparison of multiparametric MRI modalities to discriminate prostate cancer tumours

R. E. Gutiérrez-Carvajal; A. Fargeas; K. Gnep; Y. Rolland; O. Acosta; R. de Crevoisier

doi:10.1117/12.2072549

28 January 2015 A comparison of multiparametric MRI modalities to discriminate prostate cancer tumours

R. E. Gutiérrez-Carvajal, A. Fargeas, K. Gnep, Y. Rolland, O. Acosta, R. de Crevoisier

Proceedings Volume 9287, 10th International Symposium on Medical Information Processing and Analysis; 92870C (2015) https://doi.org/10.1117/12.2072549
Event: Tenth International Symposium on Medical Information Processing and Analysis, 2014, Cartagena de Indias, Colombia

Abstract

Using multiparametric MRI (mpMRI) protocols to monitor prostate cancer could provide new insights into the biological mechanisms of developing tumours. Automatically discriminating tumour regions active area of research due to the complexity and plurality of cancer behaviour. This work evaluates four different Magnetic Resonance Imaging (MRI) image modalities, namely: Diffusion-Weighted Imaging evaluated at b = {0, 100, 1000}, Apparent Diffusion Coefficient and Dynamic Contrast Enhanced MRI, by extracting texture and functional features and then selecting the optimal ones to discriminate anatomical prostate regions in each modality. The images used were taken prior to radiotherapy from eight patients previously diagnosed with moderate risk of recurrent cancer. Finally, we compared the relevance of each modality to discriminate between healthy tissue and tumour cells.

Citation Download Citation

R. E. Gutiérrez-Carvajal, A. Fargeas, K. Gnep, Y. Rolland, O. Acosta, and R. de Crevoisier "A comparison of multiparametric MRI modalities to discriminate prostate cancer tumours", Proc. SPIE 9287, 10th International Symposium on Medical Information Processing and Analysis, 92870C (28 January 2015); https://doi.org/10.1117/12.2072549

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