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7 February 2023 Infrared light effects on coenzyme binding and cellular metabolism
Jocelyn Martinez, Anna Theodossiou, Alex J. Walsh
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Proceedings Volume PC11958, Optical Interactions with Tissue and Cells XXXIII; and Advanced Photonics in Urology; PC1195807 (2023) https://doi.org/10.1117/12.2608239
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Through the induction of a fast thermal gradient, short pulses of infrared light provide a label-free method to stimulate and inhibit action potentials in neurons, but the biophysical effects that underlie this phenomenon are poorly understood. To understand this phenomenon, a computational model of metabolic rates and coenzyme binding dynamics in response to infrared light exposure was developed to investigate the effects of infrared light on cellular metabolism. The resulting model will facilitate our understanding of infrared neural stimulation to accelerate the development of infrared-light technologies which provide a noninvasive, nongenetic, and reversible method to stimulate or inhibit nerve activity.
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Jocelyn Martinez, Anna Theodossiou, and Alex J. Walsh "Infrared light effects on coenzyme binding and cellular metabolism", Proc. SPIE PC11958, Optical Interactions with Tissue and Cells XXXIII; and Advanced Photonics in Urology, PC1195807 (7 February 2023); https://doi.org/10.1117/12.2608239
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KEYWORDS
Infrared radiation
Mode conditioning cables
Infrared imaging
Short wave infrared radiation
Infrared technology
Neurons
Thermal modeling
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