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In OAT breast imaging, the optical fluence distribution in the breast under the skin layer is influenced by the melanin concentration in the epidermis. However, the extent to which skin color affects the ability to detect lesions and estimate physiological parameters in OAT breast imaging remains relatively unexplored. To address this, for the first time, realistic virtual imaging studies were conducted to assess the impact of skin color on 3D breast OAT. These studies quantitatively revealed the extent to which skin color diminishes the optical fluence within breast tissue and degrades the signal-to-noise ratio of lesions at various depths.
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Seonyeong Park, Umberto Villa, Alexander Oraevsky, Mark Anastasio, "Numerical investigation of impact of skin phototype on three-dimensional optoacoustic tomography of the breast," Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123790E (9 March 2023); https://doi.org/10.1117/12.2650740