An affordable miniaturized speckle contrast diffuse correlation tomography (scDCT) device for 2D mapping of cerebral blood flow

Fatemeh Hamedi; Chong Huang; Faezeh Akbari; Xuhui Liu; Mehrana Mohtasebi; Chaebeom Yeo; Lei Chen; Guoqiang Yu

doi:10.1117/12.3001780

13 March 2024 An affordable miniaturized speckle contrast diffuse correlation tomography (scDCT) device for 2D mapping of cerebral blood flow

Fatemeh Hamedi, Chong Huang, Faezeh Akbari, Xuhui Liu, Mehrana Mohtasebi, Chaebeom Yeo, Lei Chen, Guoqiang Yu

Author Affiliations +

Proceedings Volume PC12827, Multiscale Imaging and Spectroscopy V; PC128270E (2024) https://doi.org/10.1117/12.3001780
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We developed and evaluated a low-cost, miniaturized, and user-friendly speckle contrast diffuse correlation tomography (scDCT) device for noncontact, fast, high-density, and depth-sensitive imaging of CBF distribution in the brain. The new low-cost portable scDCT device was evaluated against an established large scDCT system using head-simulating phantoms with known optical properties and the mouse with transient ligations of common carotid arteries. Results taken from the two scDCT systems were highly consistent. The low-cost miniaturized scDCT has the potential to be commercialized as an affordable, portable, and ergonomic brain monitoring tool for neuroscience research in numerous academic and industrial laboratories.

Conference Presentation

Citation Download Citation

Fatemeh Hamedi, Chong Huang, Faezeh Akbari, Xuhui Liu, Mehrana Mohtasebi, Chaebeom Yeo, Lei Chen, and Guoqiang Yu "An affordable miniaturized speckle contrast diffuse correlation tomography (scDCT) device for 2D mapping of cerebral blood flow", Proc. SPIE PC12827, Multiscale Imaging and Spectroscopy V, PC128270E (13 March 2024); https://doi.org/10.1117/12.3001780

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