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Intraocular pressure is the main risk factor for glaucoma and is primarily regulated by resistance in the conventional outflow pathway. Although visualizing the anatomical structure of the outflow pathway has the potential to guide glaucoma treatment, noninvasive imaging of the outflow pathway is difficult owing to its small size and deep position within the sclera. To address challenges in imaging the outflow pathway, we developed a robotic visible-light optical coherence tomography system. We reconstruct the full 360 degrees of the pathway, finding segmental anatomical differences in the anatomical structure.
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Raymond Fang, Pengpeng Zhang, Tingwei Zhang, Daniel Kim, Edison Sun, Alex Huang, Cheng Sun, Hao Zhang, "Imaging the conventional outflow pathway with robotic visible-light optical coherence tomography," Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128302D (13 March 2024); https://doi.org/10.1117/12.3005174