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13 March 2024 Combined ionizing radiation acoustic and ultrasound dual-modality volumetric imaging for mapping the dose on anatomical structure during radiation therapy
Wei Zhang, Ibrahim Oraiqat, Yaocai Huang, Kaiwei Chang, Muhammad B. Alli, Dale Litzenberg, Scott Hadley, Christopher Tichacek, Eduardo Moros, Man Zhang, Paul Carson, Kyle Cuneo, Issam EI Naqa, Xueding Wang
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Proceedings Volume PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024; PC1284210 (2024) https://doi.org/10.1117/12.3000234
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Accurate dose definition is vital for ensuring optimal radiation therapy (RT) outcomes. The combination of ionizing radiation acoustic imaging (iRAI) and volumetric ultrasound imaging (US) holds the potential for real-time and precise determination of the radiation dose on anatomical structures. We developed an iRAI-US dual-modality system, utilizing a custom 2D matrix array transducer for iRAI and a commercial 2D MAT for US. The studies on phantoms quantified the system performance, and then the experiments using a rabbit liver model in vivo achieved online monitoring of dose on anatomy during RT in real time. These findings demonstrated the potential of iRAI-US combined imaging for personalized RT with improved efficacy and safety.
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Wei Zhang, Ibrahim Oraiqat, Yaocai Huang, Kaiwei Chang, Muhammad B. Alli, Dale Litzenberg, Scott Hadley, Christopher Tichacek, Eduardo Moros, Man Zhang, Paul Carson, Kyle Cuneo, Issam EI Naqa, and Xueding Wang "Combined ionizing radiation acoustic and ultrasound dual-modality volumetric imaging for mapping the dose on anatomical structure during radiation therapy", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC1284210 (13 March 2024); https://doi.org/10.1117/12.3000234
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KEYWORDS
Anatomy
Radiotherapy
Biological imaging
Ionizing radiation
Ultrasonography
Acoustics
Imaging systems
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