An ultrasensitive plasmonic biosensor for detecting various Anaemic conditions in human blood

R. Runthala; P. Raghunath; S. Mehta; P. Arora

doi:10.1117/12.3021479

6 June 2024 An ultrasensitive plasmonic biosensor for detecting various Anaemic conditions in human blood

R. Runthala, P. Raghunath, S. Mehta, P. Arora

Proceedings Volume PC12991, Nanophotonics X; PC129911T (2024) https://doi.org/10.1117/12.3021479
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Conference Poster

Abstract

We propose a highly efficient Surface Plasmon Resonance (SPR)-based sensing device to detect various anaemic conditions in human blood. A thin aluminum (Al) metal-coated glass prism is used to excite surface plasmons. A high-dielectric constant material, TiO2, is used over Al-metal to enhance the sensitivity, and a layer of fluorinated graphene (FG) is used as a bio-recognition element to study biomolecular interactions. To demonstrate sensing application, an Al (30 nm)-based engineered plasmonic device with an optimized value of TiO2 (2nm) and functionalized with an FG layer is utilized to detect various hemoglobin (Hb) concentrations in human blood at a wavelength of 1550 nm. A value of sensitivity of 123 °/RIU and FOM 439 RIU-1 is observed for the proposed Al-TiO2-FG-based SPR sensor. The proposed sensing device can be used as a biosensor to detect anemia by accurately evaluating the level of Hb concentration, making it the best candidate for biomedical applications.

Citation Download Citation

R. Runthala, P. Raghunath, S. Mehta, and P. Arora "An ultrasensitive plasmonic biosensor for detecting various Anaemic conditions in human blood", Proc. SPIE PC12991, Nanophotonics X, PC129911T (6 June 2024); https://doi.org/10.1117/12.3021479

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